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What is nSTRIDE APS?

nSTRIDE autologous protein solution (APS) is a groundbreaking new treatment for patients with arthritis. Similar to treatment with PRP (Platelet Rich Plasma) a sample of blood is used and prepared in a centrifuge. The early scientific results are promising. Particularly patients with arthritis who would otherwise require joint replacement surgery can benefit from an injection with nSTRIDE APS.

How does it work?

A blood sample is obtained and centrifuged, resulting in a fluid sample containing a high concentration of growth factors, anti-inflammatory cytokines and white blood cells. The main difference between PRP and APS is the high concentration of white blood cells in APS. This reduces inflammation and blocks the degenerative processes in the joint. APS has been shown to reduce the production of proteins that result in inflammation and joint pain.

For which conditions is nSTRIDE APS used for?

This works best for patients with mild and moderate osteoarthritis.

How many injections do I need?

A single injection with APS should give long-lasting pain relief. If and when the effect wears out, the procedure can be safely repeated.

What happens on the day?

The procedure in carried out in our treatment room. The doctor will take a small sample from a vein in your arm. While the blood sample is spun in a centrifuge, you will receive an injection with local anaesthetic to numb the target area. Once the APS is ready, the area of interest will be cleansed with an antiseptic solution. The APS will then be injected into the joint or tendon under Ultrasound guidance. The whole procedure takes approximately 30 minutes.

What happens following the APS injection?

A small dressing will cover the injection site. You should be able to go home straight away. You may experience mild pain in the first 24-48 hours following the treatment. An icepack or simple painkillers like Paracetamol should keep you comfortable.

Any restrictions following the PRP injection?

Since mild aches are common following the treatment, it’s best to take it easy for a couple of days. You can then mobilise as pain allows.

How soon before I notice the benefits?

APS stimulates a powerful healing response, which will take a short while to make a difference. As a rule of thumb, you should notice an improvement in your symptoms within 2-6 weeks following the treatment.

What are the likely outcomes?

Research suggests that the improvement can last for up to 12, sometimes even 24 months. While most patients notice the benefits of the treatment within the first 2 months, there is no success guarantee.

Will treatment with APS cure OA?

Unfortunately, there is no cure for osteoarthritis. But treatment with APS can reduce pain from arthritis by slowing down inflammatory and degenerative processes. This results in an improvement of symptoms like pain and mobility.

Is the treatment safe?

Yes. Since APS only contains concentrated parts of your own blood, the treatment is very safe. Some patients may experience mild discomfort for 1-2 days following the injection. Infection is a very rare problem and accidental damage to nerves or vessels nearby is very rare.

When should APS not be used?

Patients with blood abnormalities like anaemia or a low platelet count are not suitable for PRP injection treatment. In the presence of acute infection or active cancer it is best not to use PRP.

Will I need Physio?

You will require Physiotherapy to support the rehab process, this will be an integral part of your treatment. Our experienced Physiotherapists will discuss your rehab needs with you and will liaise with your own Physio if required.

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  • Manchester Orthopaedic Group